The Director of the Fundus Center of Zhongshan Ophthalmic Center
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 61
- 试验地点
- 1
- 主要终点
- Ultra-widefield fluorescein angiography findings at the far peripheral retina of normal eyes
研究概览
简要总结
PURPOSE: To characterize the appearance of the far peripheral retina of normal eyes using ultra-widefield fluorescein angiography (UWFA).
DESIGN: Prospective observational case series. METHODS: This study enrolled normal eyes with best corrected visual acuity ≥ 20/20, refractive error < 3.00D, and without visible retinal pathologic changes under a slit lamp-based condensing lens. The far peripheral retina was detected by UWFA. Ciliary body thickness (CBT) at 3 mm (CBT1) and 2 mm (CBT2) posterior to the scleral spur was measured by ultrasound biomicroscopy.
详细描述
PURPOSE: To characterize the appearance of the far peripheral retina of normal eyes using ultra-widefield fluorescein angiography (UWFA).
DESIGN: Prospective observational case series. METHODS: This study enrolled normal eyes with best corrected visual acuity ≥ 20/20, refractive error < 3.00D, and without visible retinal pathologic changes under a slit lamp-based condensing lens. Demographic and clinical data such as age, sex, and reasons for undergoing FA were collected. The far peripheral retina was detected by UWFA. The fundal fields obtained using the Heidelberg ultra-widefield lens in a single shot and in montage images were compared with those acquired using the Heidelberg conventional 55° lens. The signs at the peripheral retina detected by UWFA were described and grouped. Ciliary body thickness (CBT) at 3 mm (CBT1) and 2 mm (CBT2) posterior to the scleral spur was measured by ultrasound biomicroscopy.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- — 至 70 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •best corrected visual acuity ≥ 20/20
- •refractive error < 3.00D
- •without visible retinal pathologic changes under a slit lamp-based condensing lens
排除标准
- •history of ocular surgery
- •presence of ocular or systemic diseases
- •opacity of refractive media, which interfered with the peripheral retina image quality
结局指标
主要结局
Ultra-widefield fluorescein angiography findings at the far peripheral retina of normal eyes
时间窗: from November 2014 to January 2016
次要结局
- Ciliary body thickness(from November 2014 to January 2016)
研究者
Lin Lu
the Director of the Fundus Center of Zhongshan Ophthalmic Center
Sun Yat-sen University