KCT0005870
Active, not recruiting
未知
Study of Upfront surgery versus Neoadjuvant Chemotherapy Followed by Interval Debulking Surgery for Patients with Stage IIIC and IV Ovarian Cancer
ConditionsNeoplasms
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Neoplasms
- Sponsor
- Seoul National University Hospital
- Enrollment
- 456
- Status
- Active, not recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •3\.1\.1 Women aged \= 18 years.
- •3\.1\.2 Pathologic confirmed stage IIIC and IV epithelial ovarian cancer, fallopian tube cancer or
- •primary peritoneal carcinoma (diagnosis by biopsy or fine needle aspiration\*). Laparoscopic
- •biopsy with pictures is recommended.
- •\* If fine needle aspiration (FNA) showing an adenocarcinoma, patients should satisfy the
- •following conditions: a. the patient has a pelvic mass, and b. omental cake or other metastasis
- •larger than 2 cm in the upper abdomen, or pathologic confirmed extra\-abdominal metastasis,
- •and c. serum CA125/CEA ratio\>25\. If serum CA125/CEA ratio \<25 or malignancies of other
- •origins, such as breasts and digestive tract, are suspected from symptoms, physical
- •examinations or imaging diagnosis, endoscopy or ultrasonography should be done to exclusive
Exclusion Criteria
- •3\.2\.1 Patients with non\-epithelial tumors as well as borderline tumors.
- •3\.2\.2 Low\-grade carcinoma. (09/22/2016\)
- •3\.2\.3 Mucinous ovarian cancer.
- •3\.2\.4 Synchronous or metachronous (within 5 years) malignancy other than carcinoma in situ.
- •3\.2\.5 Any other concurrent medical conditions contraindicating surgery or chemotherapy that could
- •compromise the adherence to the protocol.
- •3\.2\.6 Other conditions, such as religious, psychological and other factors, that could interfere with
- •provision of informed consent, compliance to study procedures, or follow\-up.
Outcomes
Primary Outcomes
Not specified
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