Comparison of Therapeutic Effect of Mucoadhesive Nano-Triamcinolone Gel and Conventional Triamcinolone Gel on Oral Lichen Planus
Phase 3
- Conditions
- Oral Lichen Planus.
- Registration Number
- IRCT20181226042133N1
- Lead Sponsor
- Artesh University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Definite Diagnosis of Lichen Planus via Clinial criteria and Histopathology approvement
Range of 17 to 70 years old
The clinical scores of OLP were evaluated on a Thongprasom scale, which categorizes the phenotype of OPL lesions and includes 6 grades (zero = perfectly healthy, 1 = mild white lines without inflammatory regions, 2 = white lines with atrophic regions smaller than 1 cm2, 3 = white lines with atrophic regions larger than 1 cm2, 4 = white lines accompanied with erosive regions less than 1 cm2, 5 = white lines with erosive areas larger than 1 cm2
Completion of Written Consent
Exclusion Criteria
Breastfeeding
usage of Drugs that cause Lichenoid Reactions
usage of Immuno supressor Drugs
Sensitivity to Corton
Denture Usage
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The severity of pain, the size of lesions , Thongprasom scale. Timepoint: days of 2-4-6-14. Method of measurement: The severity of pain was evaluated through 100 mm visual analogue scale, the size of lesions was measured with paper lace, and the appearance of lesions was examined adopting Thongprasom scale.
- Secondary Outcome Measures
Name Time Method