Plasma Oxalate in Patient With Short Bowel

Completed

• Conditions: Short Bowel Syndrome; Hyperoxaluria; Hyperoxalemia

• Registration Number: NCT04119765
• Lead Sponsor: Hospices Civils de Lyon

Brief Summary

Hyperoxaluria due to fat malabsorption is seen in patients suffering from short bowel and can lead to stones and nephrocalcinosis. Not all patients are prone to these renal complications. only urinary oxaluria is measured in practice. Plasma oxalate shouldn't increase theoretically in these patients. However recent report showed an increase of plasma oxalate in patient with enteric hyperoxaluria. The aim of this study is to assess the plasma oxalate distribution in this specific population to have a new tool to predict renal complication of these patients.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2019-10-07
• Study First Submitted QC: 2019-10-07
• Study First Posted: 2019-10-08
• Study Start: 2020-02-27
• Primary Completion: 2022-05-04
• Study Completion: 2022-05-04
• Status Verified: 2022-07
• Last Update Submitted: 2022-07-20
• Last Update Posted: 2022-07-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 47

Inclusion Criteria

• Age ≥ 18 years
• Type II short bowel for more than 6 months
• Affiliated to a social health care

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Exclusion Criteria

• Primary hyperoxaluria
• Other type of short bowel than type II
• Minor patient or major patient protected by the law

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Plasma oxalate rate (oxalemia)	at inclusion	this sample measures the plasma oxalate rate

Trial Locations

Locations (1)

Nephrology Department, Edouard Herriot Hospital; 🇫🇷 Lyon, France