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Clinical Trials/NCT04573101
NCT04573101
Completed
Not Applicable

An EEG-based Exploration of the Variables Affecting Cortical Responses to Arabic Music Scales for a Personalised and Effective Music Therapy in the Middle East: a Clinical Study

Weill Cornell Medical College in Qatar1 site in 1 country42 target enrollmentFebruary 11, 2019
ConditionsHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Weill Cornell Medical College in Qatar
Enrollment
42
Locations
1
Primary Endpoint
Quantification of brain waves
Status
Completed
Last Updated
3 years ago

Overview

Brief Summary

Recent studies showed that various factors can contribute to the efficiency of a music therapy such as the type of music used, the type of instrument, the ethnicity, musical preference of the subjects and many others. Investigators noticed that most of studies and clinical trials, while acknowledging the importance of ethnicity and musical preferences, use the Western Music type in their investigations and practice. While in the Middle East, Music Therapy played a tremendous role in the 10th century since the "scales theory" of the famous Scientists El Farabi and Avicenna, very little countries of the Middle East are investing in scientific studies using Arabic Music as a therapeutic tool. This study will be an electroencephalogram (EEG)-based investigation on correlations of multiple factors that can influence the cortical responses of the subject to the music and self-reported state of emotion and anxiety.

Detailed Description

This is the first clinical study involving Music in Qatar and the Gulf region, and the first study to explore Arab Music Scales using a combination of EEG and self-reported assessements. Using EEG, investigators will analyze the full brain activity of brainwaves produced by up to 100 subjects in response to the audio musical stimuli. 24 different audio recordings have been designed to investigate on different acoustic cues: * with versus without quartertones * known music versus improvisation * Maqam Saba (sad) versus maqam Kurd (happy) * 3 different Middle Eastern instruments: Ney, Oud and Qanun * Two pitches: from Re or from Sol The presentation of the audio stimuli clips will be randomized by the SuperLab5 software and EEG brainwaves will be recorded using the Power Lab (AD instrument). Between every audio clip, recording will be paused to ask the subjects to self-report on their emotional and anxiety states using a self-evaluation questionnaire. Subjects will be randomly assigned to morning of afternoon sessions of recording. Using bioinformatic tools, investigators will perform a correlation study between EEG results, emotional self-report from the PANAS-X questionnaire, as well as answers to another questionnaire asking for their age, gender, ethnicity, right or left handedness, musical preferences, and if the subject plays an instrument. The outcomes will have direct applications on the development of personalized Music Therapy in the region for treatment and management of mental health conditions, neurodegenerative diseases and other conditions that are of high prevalence in the region.

Registry
clinicaltrials.gov
Start Date
February 11, 2019
End Date
September 20, 2022
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
All

Investigators

Sponsor
Weill Cornell Medical College in Qatar
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Age: 18 years old to or above (might include pregnant women)
  • Living in Qatar
  • Understand either English or arabic

Exclusion Criteria

  • Individuals not meeting the inclusion criteria
  • Individuals with auditory impairments
  • Individuals with any known neurological condition (including epilepsy, Alzheimer, Parkinson, Autism etc)
  • Individuals not able to come to the site (WCMQ).
  • Adults not able to consent

Outcomes

Primary Outcomes

Quantification of brain waves

Time Frame: During the intervention (an average of 30 minutes)

Relative power of each of the brainwaves (alpha, beta, gamma, theta, delta).

Quantification of selected emotions

Time Frame: immediately after each intervention

Count of every emotion (selected by participant from the provided Table)

Study Sites (1)

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