Effect of pentoxifylline on inflammatory factors and quality of life in hemodialysis patients

Not Applicable

Recruiting

Conditions: End Stage Renal Disease.
Chronic kidney disease, stage 5
N18.5

Registration Number: IRCT20170609034406N3

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

CRP>1
Age over 18 years
Initiate hemodialysis for at least 3 months and three times a week
Ability to understand and sign a consent form
Properly functioning arteriovenous fistula or catheter
Dialysis adequacy above 1.2

Exclusion Criteria

Pregnancy
The presence of any chronic,active,uncontrolled or severe chronic inflammatory disease(autoimmune disease,connective tissue disease,malignancy,HIV,liver disaese and pulmonary disease)
The presence of chronic infection or the occurrence of acute infection in a recent month
Hemoglobin is less than 10g/dL
Concurrently presence in another trial(drug or supplement)
A medical history(such as heart attack or brain injury)or sergical in the last 3 months
Symptoms of malabsorption
Bleeding disorders(Includes coagulopathies)or high risk of bleeding
Change in diet in the last 1 month
Abuse of alcohol and other substances that cause dependence

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum level of TNF-a. Timepoint: Before intervention. At the end of the intervention. Method of measurement: ELISA kit.;Serum level of CRP. Timepoint: Before intervention. At the end of the intervention. Method of measurement: ELISA kit.

Secondary Outcome Measures