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Clinical Trials/NCT03718637
NCT03718637
Recruiting
Phase 4

Efficacy Evaluation of Surgical Treatment Using Bioinductive Implant for Tennis Elbow (Lateral Epicondylitis)

Henry Ford Health System1 site in 1 country40 target enrollmentApril 17, 2019

Overview

Phase
Phase 4
Intervention
Lateral Epicondylectomy
Conditions
Tennis Elbow
Sponsor
Henry Ford Health System
Enrollment
40
Locations
1
Primary Endpoint
Visual Analog Scale (VAS) for Pain
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

The investigators are testing the efficacy of a new, FDA-approved bioinductive patch in lateral epicondylitis (tennis elbow) patients. A bioinductive patch is an implant that may foster tendon regrowth and healing following surgery. Patients will be randomize into one of two groups: control and investigational. Patients in the "control group" will receive the normal surgery for patients who do not respond to physical therapy, lifestyle changes, and anti-inflammatory treatment. Patients in the "experimental group" will receive the same surgical treatment, with the addition of the bioinductive patch. This patch will be implanted during surgery. Then, using a combination of ultrasound studies and other measures, the investigators will assess how well the patch works compared to surgery alone.

Detailed Description

A bioinductive patch is an implant that may foster tendon regrowth and healing following surgery. Patients will be randomized into one of two groups: control and investigational. All surgical patients will have failed non surgery options for 6 months (physical therapy, lifestyle changes, anti-inflammatories, injections) Patients in the "control group" will receive the standard surgery (open lateral epicondylectomy) . Patients in the "experimental group" will receive the same surgical treatment, with the addition of the bioinductive patch. This patch will be implanted during surgery. Then, using a combination of ultrasound studies and other measures, the investigators will assess how well the patch works compared to surgery alone.

Registry
clinicaltrials.gov
Start Date
April 17, 2019
End Date
January 17, 2027
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Stephanie Muh, MD

Deputy Service Chief, Principal Investigator

Henry Ford Health System

Eligibility Criteria

Inclusion Criteria

  • Diagnosis of lateral epicondylitis (tennis elbow) that has failed conservative treatment (Physical therapy, activity change, anti-inflammatory treatment.

Exclusion Criteria

  • Previous surgery on the currently-affected elbow.

Arms & Interventions

Control

Surgical treatment alone, consisting of tendon debridement and repair. Ultrasounds preoperatively and 6 months postoperatively.

Intervention: Lateral Epicondylectomy

Control

Surgical treatment alone, consisting of tendon debridement and repair. Ultrasounds preoperatively and 6 months postoperatively.

Intervention: Ultrasound Imaging

Experimental

Identical surgical treatment plus Smith \& Nephew bio-inductive patch implant. Ultrasounds preoperatively and 6 months postoperatively.

Intervention: Smith & Nephew Bioinductive Implant

Experimental

Identical surgical treatment plus Smith \& Nephew bio-inductive patch implant. Ultrasounds preoperatively and 6 months postoperatively.

Intervention: Lateral Epicondylectomy

Experimental

Identical surgical treatment plus Smith \& Nephew bio-inductive patch implant. Ultrasounds preoperatively and 6 months postoperatively.

Intervention: Ultrasound Imaging

Outcomes

Primary Outcomes

Visual Analog Scale (VAS) for Pain

Time Frame: Preoperative to 1 year postoperative

Traditional 1 to 10, subjective rating of pain the patient is experiencing

PROMIS CAT Scores

Time Frame: Preoperative to 1 year postoperative

A short 5 minute survey asking questions about physical function, pain, and mental health

Range of Motion

Time Frame: Preoperative to 1 year

Standard range of motion values collected by the surgeon during preoperative and followup visits

Study Sites (1)

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