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Clinical Trials/NCT06473558
NCT06473558
Not yet recruiting
Not Applicable

Identification of Depressive and Anxiety Symptoms Among a Sample of Emergency Department Patients Using Artificial Intelligence (AI) Technology

University Hospitals Cleveland Medical Center1 site in 1 country30 target enrollmentJanuary 1, 2026

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Artificial Intelligence (AI)
Sponsor
University Hospitals Cleveland Medical Center
Enrollment
30
Locations
1
Primary Endpoint
Percentage of participants who score 10-14 on the PHQ-9
Status
Not yet recruiting
Last Updated
9 months ago

Overview

Brief Summary

Behavioral health problems, such as depression and anxiety, are common yet often are not identified by emergency department doctors and nurses. These mental health conditions can be due to medical issues or can worsen medical problems. One way investigators hope to do a better job of learning about mental health is by training Artificial Intelligence (AI) software to detect anxiety and depression by analyzing facial expression and tone of voice.

Participants are invited to participate in a study which may help improve emergency department care. An audio and video recording of the participant's responses to some simple, non-psychological questions will be analyzed by a computer to determine whether investigators can assess mood and anxiety by analyzing speech and visual patterns. The audio and video will not be listened to nor watched by study personnel, only analyzed by a computer. The investigator's hope is that it will help others in the future by aiding in the assessment of psychological state. This study is being conducted at CMC ED only.

Registry
clinicaltrials.gov
Start Date
January 1, 2026
End Date
August 30, 2026
Last Updated
9 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Adult patients (age 18 and over) who presents to the UHCMC ED voluntarily with no obvious psychological disturbance by self-report or nurse/provider initial assessment
  • English-speaking
  • Patients with non-emergent concerns of Emergency Severity Index (ESI) level 3, 4, or 5

Exclusion Criteria

  • Prisoners
  • Patients who are deemed to be critically ill (including life or limb threatening illness) or unable to consent
  • Non-English Speaking

Outcomes

Primary Outcomes

Percentage of participants who score 10-14 on the PHQ-9

Time Frame: Baseline

Patient Health Questionnaire (PHQ-9) is a multipurpose instrument for screening, diagnosing, monitoring, and measuring severity of depression. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Number of participants that AI screened positive for moderate depression symptoms.

Time Frame: Baseline

Number of participants that AI screened positive for moderate anxiety symptoms.

Time Frame: Baseline

Percentage of participants who score 5-9 on the PHQ-9

Time Frame: Baseline

Patient Health Questionnaire (PHQ-9) is a multipurpose instrument for screening, diagnosing, monitoring, and measuring severity of depression. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Number of participants that AI screened positive for severe depression screening

Time Frame: Baseline

Number of participants that AI screened positive for mild anxiety symptoms.

Time Frame: Baseline

Number of participants that AI screened positive for severe anxiety symptoms.

Time Frame: Baseline

Percentage of participants who score 15-19 on the PHQ-9

Time Frame: Baseline

Patient Health Questionnaire (PHQ-9) is a multipurpose instrument for screening, diagnosing, monitoring, and measuring severity of depression. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Percentage of participants who score 20-27 on the PHQ-9

Time Frame: Baseline

Patient Health Questionnaire (PHQ-9) is a multipurpose instrument for screening, diagnosing, monitoring, and measuring severity of depression. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Percentage of participants who score 5-9 on the GAD-7

Time Frame: Baseline

Generalized Anxiety Disorder (GAD-7) is a easy to preform initial screening tool for generalized anxiety disorder. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Percentage of participants who score 10-14 on the GAD-7

Time Frame: Baseline

Generalized Anxiety Disorder (GAD-7) is a easy to preform initial screening tool for generalized anxiety disorder. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Percentage of participants who score above 15 on the GAD-7

Time Frame: Baseline

Generalized Anxiety Disorder (GAD-7) is a easy to preform initial screening tool for generalized anxiety disorder. Questions are scored on a Likert scale of 0-3 with 0 being not at all and 3 being nearly every day.

Number of participants that AI screened positive for moderately severe depression symptoms.

Time Frame: Baseline

Number of participants that AI screened positive for mild depression symptoms.

Time Frame: Baseline

Study Sites (1)

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