MR Guidance for Liver and Pancreas
- Conditions
- Magnetic Resonance Imaging
- Interventions
- Other: MRI
- Registration Number
- NCT03582189
- Lead Sponsor
- University Health Network, Toronto
- Brief Summary
This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the radiation treatment plan.
Patients will have 5 MRIs with each of their RT sessions. If patients' RT treatment will consist of more than 5 fractions, only 5 MRIs will be done with any 5 RT fractions. Patients will be completing a short questionnaire at the end of each MRI. A patient questionnaire will also be completed at the end of the study to assess for patient satisfaction.
There will be 30 evaluable patients enrolled to the study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 30
- Patients 18 years or older
- Diagnosed with locally advanced pancreatic cancer or hepatocellular carcinoma being considered for treatment with chemoradiation, long course RT, or SBRT with curative intent or palliative intent, planned for 5 or more RT fractions
- Contraindications for MRI: ferromagnetic prosthesis, pacemaker / implanted defibrillator, claustrophobia
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Liver Metastases MRI Approximately 10 patients with liver mets will be enrolled to the study with the primary aim of determining the feasibility of using off-line MRI-guidance during the course of radiation treatment Pancreatic Cancer MRI Approximately 10 patients with pancreatic cancer will be enrolled to the study with the primary aim of determining the feasibility of using off-line MRI-guidance during the course of radiation treatment Hepatocellular carcinoma MRI Approximately 10 patients with HCC will be enrolled to the study with the primary aim of determining the feasibility of using off-line MRI-guidance during the course of radiation treatment
- Primary Outcome Measures
Name Time Method Patient Satisfaction Survey At study completion (day5 or week 5, depending on type of treatment) To evaluate patient satisfaction with the MR guidance process, a modified version of a questionnaire previously used at our institution will be performed at the end of the study
MRI-Anxiety Questionnaire Prior to or before MR session 5 (day 5 or week 5, depending on type of treatment) his instrument will be used to evaluate patient related anxiety after each MR
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University Health Network - Princess Margaret Cancer Centre
🇨🇦Toronto, Ontario, Canada