MR Guidance for Liver and Pancreas

Recruiting

• Conditions: Magnetic Resonance Imaging

• Registration Number: NCT03582189
• Lead Sponsor: University Health Network, Toronto

Brief Summary

This is a single centre, single arm, prospective feasibility study that aims to see whether magnetic resonance imaging (MRI) as a source of image guidance before each radiation treatment fraction is feasible, and also if it may provide information that could potentially be used during the treatment to improve the radiation treatment plan.

Patients will have 5 MRIs with each of their RT sessions. If patients' RT treatment will consist of more than 5 fractions, only 5 MRIs will be done with any 5 RT fractions. Patients will be completing a short questionnaire at the end of each MRI. A patient questionnaire will also be completed at the end of the study to assess for patient satisfaction.

There will be 30 evaluable patients enrolled to the study.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-05-01
• Study First Submitted QC: 2018-06-27
• Study First Posted: 2018-07-10
• Study Start: 2018-07-11
• Status Verified: 2024-06
• Last Update Submitted: 2024-06-17
• Last Update Posted: 2024-06-18
• Primary Completion: 2027-02
• Study Completion: 2027-02

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients 18 years or older
• Diagnosed with locally advanced pancreatic cancer or hepatocellular carcinoma being considered for treatment with chemoradiation, long course RT, or SBRT with curative intent or palliative intent, planned for 5 or more RT fractions

Exclusion Criteria

• Contraindications for MRI: ferromagnetic prosthesis, pacemaker / implanted defibrillator, claustrophobia

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Patient Satisfaction Survey	At study completion (day5 or week 5, depending on type of treatment)	To evaluate patient satisfaction with the MR guidance process, a modified version of a questionnaire previously used at our institution will be performed at the end of the study
MRI-Anxiety Questionnaire	Prior to or before MR session 5 (day 5 or week 5, depending on type of treatment)	his instrument will be used to evaluate patient related anxiety after each MR

Trial Locations

Locations (1)

University Health Network - Princess Margaret Cancer Centre; 🇨🇦 Toronto, Ontario, Canada