Randomized Prospective Trial on the Use of Laser Assisted Hatching (LAH) for Transfer of Frozen/Thawed Embryos in Human IVF/ICSI

Not Applicable

Completed

• Conditions: IVF; ICSI
• Interventions: Procedure: laser assisted hatching

• Registration Number: NCT00561249
• Lead Sponsor: University Hospital, Ghent

Brief Summary

At the time of transfer of frozen/thawed embryos in human IVF/ICSI, patients are randomized between study and control group.In the control group no additional intervention takes place on the embryos to be transferred,in the study group, embryos for transfer are subjected to laser assisted hatching(LAH) following the standard procedure.The LAH procedure lasts two minutes per embryo.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2007-11-16
• Study First Submitted QC: 2007-11-19
• Study First Posted: 2007-11-20
• Study Start: 2007-12
• Primary Completion: 2013-04
• Study Completion: 2013-04
• Status Verified: 2014-01
• Last Update Submitted: 2014-01-24
• Last Update Posted: 2014-01-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 293

Inclusion Criteria

• 18 years old and above
• Female

Exclusion Criteria

• No exclusion criteria, except not possible to give informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	laser assisted hatching	Embryos for transfer are subjected to laser assisted hatching(LAH) following the standard procedure.The LAH procedure lasts two minutes per embryo.

Primary Outcome Measures

Name	Time	Method
clinical implantation per transferred embryo	fourteen days after transfer

Secondary Outcome Measures

Name	Time	Method
clinical pregnancy and birth per transfer	resp. 12 weeks and 38 weeks after transfer

Trial Locations

Locations (1)

University Hospital Ghent; 🇧🇪 Ghent, Belgium