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Clinical Trials/NCT06656754
NCT06656754
Recruiting
Early Phase 1

Error-enhanced Learning & Recovery in 2 & 3 Dimensions

Shirley Ryan AbilityLab1 site in 1 country56 target enrollmentNovember 17, 2024
ConditionsStroke

Overview

Phase
Early Phase 1
Intervention
Not specified
Conditions
Stroke
Sponsor
Shirley Ryan AbilityLab
Enrollment
56
Locations
1
Primary Endpoint
Perpendicular Error
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

To determine the effects of 3D isometric movement training in healthy participants and impaired participants due to a stroke.

Detailed Description

Researchers have found that neurotypical adults are able to train movement skills when sensory sources, such as proprioception, are altered using isometric conditions and visual feedback in a two-dimensional environment.Building off this knowledge, the investigators plan to apply similar techniques to both neurotypical adults and stroke survivors with impaired movement, but in a three-dimensional environment. The investigators will ask participants to practice a unilateral virtual reality targeted reaching task using a robotic arm in a 3D visual display system mounted over the arm. Participants will be given visual feedback of their arm through a virtual avatar displayed on the screen. First, they will complete unconstrained targeted reaching and then complete targeted reaching with the robotic arm constrained in a fixed position ("isometric" movement). The forces applied to constrain the robotic arm will be translated to the virtual avatar arm on the screen, and it will look as if their arm is moving. The investigators will compare perpendicular errors (maximum difference between the ideal reaching trajectory and the actual) made in unconstrained and constrained movement conditions. The investigators aim to determine if the two movement conditions yield similar error responses when sensory sources are altered in a 3D environment.

Registry
clinicaltrials.gov
Start Date
November 17, 2024
End Date
May 1, 2029
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

James Lanphier Patton

Principal Investigator

Shirley Ryan AbilityLab

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Perpendicular Error

Time Frame: through study completion, an average of 1 year.

Maximum distance between the ideal reaching trajectory and the actual trajectory made in unconstrained and constrained movement conditions

Study Sites (1)

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