The effect of the cognitive function of GLP-1 receptor agonist in Type 2 diabtes patients with mild cognitive dysfunction. - prospective,randomized,active-controlled study
Not Applicable
- Conditions
- Type 2 diabetes with mild cognitive disfunction
- Registration Number
- JPRN-UMIN000017592
- Lead Sponsor
- Tokyo medical university, Department of Medicine, Division of Diabetes, Metabolism and Endocrinology, Department of Gerontology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1.Patients who are not Type 2 diabetes 2.Excessive common custom drinker 3.Patients having a cancer 4. Patients with severe diabetic complication. 5.Patients with severe renal disease or severe liver disease 6. History of chemical sensitivity to antidiabetic drugs. 7. Women who are pregnant or nursing or could become pregnant. 8. Determined to be ineligible by the physician in charge for any other reason.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Change of cognitive function(MMSE,DSST,Moca-J,GDS-15,TMT-A,TMT-B)
- Secondary Outcome Measures
Name Time Method Change of cerebral blood flow(MRI,SPECT) Blood glucose(HbA1c,Fasting blood glucose, post-prandial blood glucose, SMBG) Glycoalbumin, 1,5-anhydroglcitol, C-peptide, hypoglycemic episode, QOL(DTSQ)