Does duloxetine reduces pain in total knee arthroplasty? Randomized controlled trial
Phase 4
Completed
- Conditions
- pain score and function after take duloxetine compare without duloxetine groupPain, TKA, Duloxetine
- Registration Number
- TCTR20200925002
- Lead Sponsor
- none
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 42
Inclusion Criteria
OA knee who undergoing unilateral TKA
Age > 40 years
Comply with the protocol
Exclusion Criteria
Allergy to duloxetine
Allergy to medication protocol
Severe liver and renal function
Secondary OA knee
Poor control DM
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method pain score day1,3 after sugery, 2weeks, 6 weeks, 3month VAS score
- Secondary Outcome Measures
Name Time Method functional score 6weeks and 3month Oxford knee score ,KROOS,flexion of knee 6 weeks and 3 month metric,morphine consumption in hospital period metric,Adverse events 3 month Nausea ,dry lips ,dizziness ,constipation