Exploratory evaluation of the effect of cholestyramine on serum levels of persistent organic pollutants in obese patients
- Conditions
- ObesityMedDRA version: 20.0Level: PTClassification code: 10014989Term: Epidermolysis bullosa Class: 100000004850Therapeutic area: Diseases [C] - Hormonal diseases [C19]
- Registration Number
- CTIS2023-505116-37-00
- Lead Sponsor
- Centre Hospitalier Universitaire De Nice
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Female patients with an accepted indication for bariatric surgery (BMI > 40 kg/m2 or BMI > 35 kg/m2 with complication(s) improveable by surgery), Aged between 18 and 45 years, Having effective contraception (oral contraception, hormonal or non-hormonal intrauterine device, progestin implant) which will be adapted in the peri-operative period in accordance with the recommendations in force
Pregnant or breastfeeding women, Known allergy or intolerance to cholestyramine, Chronic constipation, Chronic disease that may interfere with the efficacy of treatment (unbalanced diabetes with HbA1c >7%, known and treated dyslipidaemia, chronic renal failure with GFR <60 ml/min, hepatocellular failure), Phenylketonuria, Patients on anti-vitamin K, digoxin, levothyroxine or likely to be on such therapy within 3 months of inclusion.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method