TO ASSESS EFFICACY OF PUNARNAVA MANDURA WITH AND WITHOUT SHATAVARI AVALEHA IN PREGNANCY ANAEMIA

Phase 2/3

Not yet recruiting

• Conditions: Pregnancy, childbirth and the puerperium,

• Registration Number: CTRI/2019/06/019626
• Lead Sponsor: NIA

Brief Summary

Pandu roga is one such disease which is found mentioned in Rigveda and Atharvaveda.

According to Caraka Samhita Pandu roga is a disease of rasavaha srotas. There is no direct reference of Garbhini Pandu (anaemia in pregnancy) in Ayurvediya texts. Acharya Caraka in Sharira sthana has explained about Bala varna hani of garbhini in 6th month of pregnancy, which means feeling of weakness and loss of complexion. In symptoms of 7th month Acharya Chakrapani has mentioned Shonita hinta means low blood volume. All these symptoms are present in 2nd trimester of pregnancy and may be due to anaemia and can be considered as reference for Garbhini Pandu. Acharya Harita has described eight Garbhopadravas in  Harita  Samhita  and included Vivarnatva, which appears to be pallor that accompanies anaemia.  In  the  context  of  Raktagulma, Acharya Kashyapa  has  described  furnished  similar  description during  with  Garbhavastha  (pregnancy)  which  refers  to Garbhavasthajanya  Pandu.  The growing fetus is nourished by the Rasa of mother. So, mother needs a better and more nutritious diet.

The disease Pandu has been described on the basis of its peculiar colour presentation as described by-

Pandustu   peetbhagardham ketakidhoolisannibham (Shabdarnava)

India is one of the country with high prevalence of anemia during pregnancy. Iron deficiency anaemia is most common condition occurs in pregnant women. The global prevalence of anaemia among pregnant women is 55.9%. In India, the prevalence of anaemia in pregnant women has been reported to be in range of 33% to 89%. India contributes to about 80% of the maternal deaths due to anemia in South Asia.

Anaemia is classified as mild, moderate and severe based on the concentration of haemoglobin in the blood. Mild anaemia corresponds to a level of haemoglobin concentration of 10.0-10.9 gm/dl for pregnant women and 10.0-11.9 gm/dl for non pregnant women. Moderate anaemia corresponds to a level of 7.0-9.9 gm/dl, while severe anaemia corresponds to level less then7.0 gm/dl.

Empirical use of different preparations of iron in the treatment of anaemia from ancient times is evident. Lauha Bhasma and Mandura Bhasma are effective in treating anaemia. On the basis of Pandughnata (antianaemic), Prinana(nourishing), Raktaprasadana(blood toner). Punarnava Mandura is successfully used by Ayurvediya physicians for the management of all types of Pandu and proved beneficial in Antenatal care by previous research works.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-06-15
• Last Update Posted: 2019-07-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 30

Inclusion Criteria

• A Pregnant woman with haemoglobin percentage 7.0-10.00 gm/dl, haematocrit less than 30%.
• A pregnant woman with anaemia in 13th to 28th week of pregnancy.

Exclusion Criteria

• Anaemia other than iron deficiency anaemia.
• Patients having haemoglobin percentage less than 7.0 gm/dl.
• Patients suffering from systemic diseases like Hypertension, Diabetes, Thyroid disorders, Liver disorders, Renal disorder, Cardio Vascular disorders, Cerebro-Vascular disorders, Tuberculosis etc.
• Patients suffering from pregnancy related complications such as pregnancy induced hypertension, pre- eclampsia, eclampsia, hyper emesis gravidarum, gestational diabetes etc.
• Pregnancy associated with Rh Incompatibility, Jaundice, Ovarian tumour, Placenta Previa, Abruptio Placenta.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess the efficacy of Punarnava Mandura with and without Shatavari Avaleha in the management of Garbhini Pandu with special reference to improvement in haemoglobin percentage.	To assess the efficacy of Punarnava Mandura with and without Shatavari Avaleha in the management of Garbhini Pandu with special reference to improvement in haemoglobin percentage.Duration- 2 months

Secondary Outcome Measures

Name	Time	Method
To assess the efficacy of Punarnava Mandura with and without Shatavari Avaleha in the management of Garbhini Pandu with special reference to improvement in haemoglobin percentage.

Trial Locations

Locations (1)

National Institute Of Ayurveda; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute Of Ayurveda

🇮🇳Jaipur, RAJASTHAN, India

Moushami Kulhare

Principal investigator

9926318857

drmoushami@gmail.com