Evaluation of Peripartum Blood Loss and Postpartum Anaemia in Macrosomia & Gemini
- Conditions
- Bloodloss in Pregnancy
- Interventions
- Other: Observation of Blood loss
- Registration Number
- NCT06201910
- Lead Sponsor
- Goethe University
- Brief Summary
Anaemia in pregnant women occurs at a haemoglobin (Hb) concentration \<11 g/dL and treatment is essential to prevent increased maternal morbidity, fetal morbidity and mortality. Studies show a distinct risk of haemorrhage in pregnant women due to increased uterine dilatation, due to twins or macrosomic singletons. Currently, prepartum anaemia management, the influence of anaemia and the administration of foreign blood concentrates are insufficiently studied. The investigators intend to conduct a monocentric retrospective analysis of this subcohort.
- Detailed Description
Patient blood management is essentially based on three pillars, and a meta-analysis has already shown that consistent use can reduce transfusions and mortality. The WHO defines anaemia in pregnant patients as a haemoglobin (Hb) concentration \<11 g/dl.
Treatment of iron deficiency anaemia is essential because data show that iron deficiency anaemia is associated with increased maternal morbidity, fetal morbidity and mortality. Studies show a separate risk of bleeding in pregnant women due to increased uterine prolapse, for example in twin pregnancies or macrosomic singletons. At present, the prepartum anaemia management of patients, the influence of anaemia and the administration of foreign blood concentrates are insufficiently studied, which the investigators intend to investigate.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 575
- Pregnancy
- pre-existing coagulation disorder
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Controll Observation of Blood loss Pregnant women without uterine dilation due to a twin pregnancy or a macrosomic singleton Makrosome Observation of Blood loss Pregnant women with uterine dilation due to a macrosomic singleton Gemini Observation of Blood loss Pregnant women with uterine dilation due to a twin pregnancy
- Primary Outcome Measures
Name Time Method Bloodloss Within the first 24 hours after delivery Blood loss measured by haemoglobin value
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
University Hospital Frankfurt
🇩🇪Frankfurt, Hessen, Germany
Goethe University
🇩🇪Frankfurt, Hessen, Germany