EUCTR2013-001835-33-FI进行中（未招募）不适用
A multicenter, randomized, double-blind, parallel group study to assess the safety and tolerability of initiating LCZ696 in heart failure patients comparing two titration regimens.
适应症
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 480
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •Age = 18 years.
- •Chronic Heart Failure with New York Heart Association class II-IV.
- •Left ventricularejection fraction = 35%.
- •Patients must be treated with beta-blockers.
- •Other protocol-defined inclusion criteria may apply.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 240
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 240
排除标准
- •Potassium > 5.2 mmol/l.
- •Estimated glomerular filtration rate < 30 ml/min/1.73 m2.
- •Systolic blood pressure <100 mmHg or > 180 mmHg.
- •History of intolerance to recommended target doses of angiotensin converting enzyme inhibitors or angiotensin receptor blockers.
- •Other protocol-defined exclusion criteria may apply.
研究者
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