IRCT201705309472N13招募中2 期
Effect of saffron powder on serum concentration of hs-CRP, TNF-a, MDA, TAC, adiponectin and leptin in patients with non-alcoholic fatty live disease
Deputy of Research of Iran University of Medical Sciences0 个研究点目标入组 76 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 76
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •Inclusion criteria
- •1- Age 18 to 65 years
- •2. Both sexes
- •3. Detection of non-alcoholic fatty liver by an expert physician based on the high levels of ALT, AST enzymes
- •>=30U / L in men and> 19U/L in women) and liver transcription
- •4. Desire to participate in studying and signing conscientious intention
- •Non-inclusion criteria: (exclusion criteria)
- •1- Pregnancy and lactation or planning pregnancy
- •2- Use an antioxidant supplement or any nutritional supplement within one month before sampling
- •3. Acute heart disease, kidney, thyroid, diabetes, infections, hepatitis B and C and other liver diseases (diagnosed by a specialist) and diseases that affect the weight (hyperprolactinemia, Cushing's syndrome)
- •4. Have a high-gain or weight loss regimen within 3 months prior to sampling
- •5- Using effective drugs on weight, fatty liver and insulin resistance during 3 months before sampling (hormonal, antidepressant, anti-psychotics)
- •6- Use of drugs that are probably related to NAFLD:
- •7- (valporic acid, tetracycline, systematic glucocorticoid, methotrexate amidarone, anabolic steroids, estrogen, tamoxifen or other known hepatotoxic drugs)
- •Exit criteria:
- •1. Unwillingness to continue cooperation in research
- •2- Initiating the use of anti-NASH drugs (thiazolidindiones, vitamin E, betaine, milk thistle, UDCA, SAM-E, gemfibrozil, probiotic, anti-TNF-a)
- •3. Start using any type of nutritional supplement and anti-inflammatory drugs
- •4. Cure for diseases that require special treatments that interfere with the intervention.
- •5- Pregnancy during the study
- •6- Patients whose compliance and consumption of saffron powder or placebo by them is less than 80% recommended by the host.
排除标准
- 未提供
研究者
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