The effect of probiotics on depressive symptoms in depressed patients - The effect of probiotics on depressive symptoms in depressed patients

ational Center of Neurology and Psychiatry0 个研究点目标入组 22 人开始时间: 2018年6月1日最近更新: 2023年10月17日

适应症

试验速览

阶段: 未知
状态: 已完成
发起方
入组人数: 22

研究概览入排标准研究者记录与标识符相似试验

研究概览

简要总结

The HAM-D21 score decreased significantly over the intervention period No statistically significant change for the percentage of subjects diagnosed with IBS. The counts of total lactobacilli and its subpopulation, Lacticaseibacillus both increased significantly after the intervention. No other bacterial targets were not significantly changed. Subgroup analyses indicated that greater exposure to Bifidobacterium and the Atopobium cluster was associated with greater reduction of depressive symptoms.

研究设计

研究类型: Interventional

入排标准

年龄范围: 20years-old 至 65years-old（—）
性别: All

入选标准

未提供

排除标准

•(1)Subjects who have a history of cardiovascular disease, liver disease, kidney disease, digestive tract disease and diabetes. (2)Subjects suspected to suffer from alcohol dependence and / or drug dependence. (3)Subjects who have a specific configuration that occur allergy and / or hypersensitivity against test drinks. (4)Marked suicidal ideation as indexed by three points or more on the "suicide" item of HAM-D. (5)Subjects who have edema in the brain. (6)Subjects who are diagnosed as a complication of dementia or intellectual disability. (7)Subjects who are lactating and/or pregnant. (8)Subjects who have a contraindication to MRI, such as claustrophobia, tattoo, implanted electrical device (e.g. cardiac pacemaker). (9)Those who have suffered serious head trauma or a central nervous system disease. (10)Subjects who are judged as unfit for the subject by the principal investigator

研究者

发起方

ational Center of Neurology and Psychiatry

相似试验

已完成

3 期

The effect of probiotic supplement on depression severityDepression.Depressive episode

IRCT201601102394N20Research Center of Iran University of Medical Sciences40

尚未招募

不适用

Effects of a probiotic food supplement on depressive symptoms in adultsSub-threshold DepressionMental Health - Depression

ACTRN12621000675820a Trobe University48

已完成

不适用

Effects of Probiotics on MoodDepression, Anxiety

NCT03539263Probiotical S.p.A.39

已完成

4 期

A clinical trial to study the effect of Probiotics in patients with Major Depressive Disorder

CTRI/2020/05/025027Deepika Bansal100

招募中

3 期

The effect of probiotics on lupusSystemic lupus erythematosus (SLE).Systemic lupus erythematosus (SLE)

IRCT20191223045865N2Bojnourd University of Medical Sciences23