CAPO: Classical Guitar to Alleviate Parkinson's Disease Symptom Onus
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Change in the motor subscore of the Movement Disorder Society Unified Parkinson's Disease Rating Scale Motor Subscale
研究概览
简要总结
The purpose of this study is to understand if training Parkinson's disease patients in classical guitar will improve motor function, mood, and quality of life. While medication has been found to be effective for many Parkinson's disease patients, many patients still have symptoms. Previous studies have found that music and rhythm-based activities can help Parkinson's disease symptoms. A previous study looked at the effect of playing classical guitar on Parkinson's disease symptoms. They found positive changes in Parkinson's disease symptoms that lasted for 6 weeks after the study ended. Further, there were positive changes in depression, anxiety, and quality of life.
详细描述
Subjects will be asked to take part in classical guitar lessons once a week for six weeks and physical therapy once a week for six weeks. There will be 40 people enrolled in the study. Twenty people will have classical guitar lessons first and physical therapy second. The other twenty people will have physical therapy first and classical guitar lessons second. The study will last a total of 12 weeks. Each session will last 1-2 hours. Sessions will be held at the Northwest Chapter headquarters of the American Parkinson's Disease Association.
Examples of the types of activities subjects will do during the physical therapy sessions include finger exercises, tasks with both hands, tasks while standing, and tasks while walking.
Examples of the types of activities you will do during the classical guitar lessons include playing chords and songs on the guitar.
Subjects will have physical exams and complete questionnaires at the beginning of the study, at six weeks, and at the end of the study.
If subjects have Apple watches, they will be asked to download an application called StrivePD on their watch and iPhone. StrivePD is an application that allows subjects to keep track of their Parkinson's disease symptoms or set medication reminders, for example. When used with an Apple watch, it can automatically record symptoms like tremors. During this study, the StrivePD application will only be used to collect data about what percentage of the day they have tremors and how much they sleep.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •50-90 years old
- •Diagnosis with Parkinson's disease by a Movement Disorder specialist
排除标准
- •Professional musician or formal music training
- •Inability to play a classical guitar physically
- •Inability to follow instruction
- •Receiving physical therapy at the time of the study
- •Unable to attend all sessions of study
结局指标
主要结局
Change in the motor subscore of the Movement Disorder Society Unified Parkinson's Disease Rating Scale Motor Subscale
时间窗: Baseline, 6 weeks, 12 weeks
Change in Parkinson's disease rating scale, range 0-32, higher score means more severe Parkinson's disease symptoms
次要结局
- Change in Parkinson's disease Questionnaire-39(Baseline, 6 weeks, 12 weeks)
- Change in Apathy evaluation scale total score(Baseline, 6 weeks, 12 weeks)
- Change in hours of sleep(Baseline, 6 weeks, 12 weeks)
- Change in percent of day with tremor(Baseline, 6 weeks, 12 weeks)
- Change in Beck Depression Inventory-II(Baseline, 6 weeks, 12 weeks)
- Change in American Parkinson's disease Association symptom tracker score(Baseline, 6 weeks, 12 weeks)
研究者
Christopher Adams
Acting Instructor
University of Washington