To check the efficiency of two different routes (into the vein and into the muscle) of a medicine that will reduce swelling, pain and improve mouth opening after wisdom tooth removal. The medicine is dexamethasone and it reduces signs of inflammation.
- Registration Number
- CTRI/2018/10/016164
- Lead Sponsor
- Mehul Saha
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
1. Impacted mandibular third molars with Pell and Gregory classification Class II or III and Level B or C on the radiograph and Pederson difficulty index of Moderately Difficult (5-6).
2. Subjects would be healthy individuals, 18 years of age or older and with AHA score I.
3. Subjects who would not require any prophylactic antibiotics or analgesics.
4. Subjects who would be travelling within 10km radius of the hospital.
1. Patients with signs of active infection (fever/pus discharge/palpable and painful lymph nodes).
2. Immunocompromised subjects.
3. Medically compromised subjects (ASA score II, III, IV, V)
4. History of allergy to the drug used.
5. Pregnancy or lactation.
6. Those who use other drugs during the observation period (anticoagulants/antiepileptics/steroids/antifungals/antibiotics/analgesics).
7. Those who refuse to take part in the study or come for regular follow up.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Facial measurement, mouth opening and pain level would be recorded pre operatively and swelling, pain and trismus would be measured on first, third and seventh postoperative days.Timepoint: Facial measurement, mouth opening and pain level would be recorded pre operatively and swelling, pain and trismus would be measured on first, third and seventh postoperative days.
- Secondary Outcome Measures
Name Time Method Evaluation of patient comfort after surgical removal of wisdom toothTimepoint: Evaluation of patient comfort on first, third and seventh day after surgical removal of wisdom tooth