跳至主要内容
临床试验/NCT07507877
NCT07507877招募中不适用

Infraclavicular Axillary Vein Collapsibility Index as a Predictor of Fluid Responsiveness in Spontaneously Breathing Patients in Sepsis-related Acute Circulatory Failure: a Prospective Observational Study

Ain Shams University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2026年4月4日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
40
试验地点
1
主要终点
The infraclavicular axillary vein collapsibility index changes in response to fluid challenge.

研究概览

简要总结

Fluid responsiveness refers to the ability of the left ventricle to significantly increase stroke volume following fluid administration, and its assessment is critical in managing acute circulatory failure while avoiding fluid overload.Infraclavicular axillary vein collapsibility index is a substitute for inferior vena cava collapsibility index in assessment for the need of fluid resuscitation in spontaneously breathing sepsis related acute circulatory failure patients.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adult patients ≥18 years.
  • Patients with sepsis must meet at least two or more criteria of systemic inflammatory response syndrome (SIRS).
  • Spontaneously breathing patients.
  • Clinical signs of acute circulatory failure.

排除标准

  • Patients below the age of 18 years.
  • Mechanically ventilated patients

结局指标

主要结局

The infraclavicular axillary vein collapsibility index changes in response to fluid challenge.

时间窗: Fluid challenge over 10 min time period.

The infraclavicular axillary vein collapsibility index changes in response to fluid challenge. A collapsibility index greater than fifty percent in spontaneously breathing patients is commonly associated with a right atrial pressure between zero and five millimeters of mercury.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ibrahim Mamdouh Esmat

Professor of Anesthesia and Intensive Care,Faculty of Medicine, Ain- shams University, Cairo, Egypt.

Ain Shams University

研究点 (1)

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