The effect of three types of aerobic, resistance, and topical specialized exercises in diabetic patients

Phase 3

Conditions: Diabetic neuropathy.
Diabetes mellitus due to underlying condition with diabetic neuropathy, unspecified
E08.40

Registration Number: IRCT20181006041252N19

Lead Sponsor: Sabzevar University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 78

Inclusion Criteria

FBS above 126 mg/dl or 2h blood glucose above 200 mg/dl
Diabetic neuropathy
Having diabetes for 4-6 years
History of Metformin use for at least 2 years
Start medication for diabetes

Exclusion Criteria

Having autonomic neuropathy, non-diabetic neuropathy
Using drugs affecting the nervous and vascular systems
Having Cardiac or musculoskeletal problems precludes activity

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Fasting blood sugar (FBS). Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;Hemoglobin A1C. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of Luminescence quantitative and ELISA methods.;The severity of diabetic neuropathy. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Use of the Michigan Neuropathy Screening Instrument (MNSI).

Secondary Outcome Measures

Name	Time	Method
The limbs blood flow. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Ankle-Brachial Index (ABI) device.;Dynamic equilibrium. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Neuron-EMG-Micro device.;The sense of vibration. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Tuning fork device.;The sense of touch. Timepoint: At the beginning of the study (before the intervention) and 2 months after the start of the training program. Method of measurement: Round bottom pin, cotton or brush.