Observational Study About In-patients Admitted With Fever

Recruiting

• Conditions: Fever

• Registration Number: NCT05422651
• Lead Sponsor: Xiangya Hospital of Central South University

Brief Summary

Fever is a common symptom in patients with infectious diseases. This study hopes to understand the epidemiological characteristics of patients hospitalized due to fever through observational research, including: clinical characteristics, etiology of fever and prognosis after treatment. So as to further search for biochemical or other serological indicators to predict the diagnosis and prognosis of infectious fever and non-infectious fever, and try to establish relevant prediction models.

Detailed Description

This study mainly prospectively analyze the clinical data of patients with fever with/without other symptoms admitted to the department of infectious diseases, Xiangya Hospital of Central South University, to analyze the epidemiological characteristics, diagnosis and prognosis of these patients. This is an observational study. All subjects will receive the currently recognized routine test of fever according to their disease and corresponding etiological treatment if needed. The researchers will collect various clinical examination indexes of the subjects in the process of diagnosis and treatment, including but not limited to white blood cells, C-reactive protein, Procalcitonin, ferritin, blood culture, therapeutic drugs, etc. Etiology and prognosis of patients will be recorded. Blood samples, urine and stool samples of all subjects will be taken after enrollment and stored for probably testing in the future. This study has no additional intervention and treatment for subjects. All subjects will sign informed consent.

Study Timeline

• Status Verified: 2022-06
• Study Start: 2022-06-01
• Study First Submitted: 2022-06-13
• Study First Submitted QC: 2022-06-13
• Study First Posted: 2022-06-16
• Last Update Submitted: 2022-06-23
• Last Update Posted: 2022-06-29
• Primary Completion: 2024-08-01
• Study Completion: 2026-08-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 500

Inclusion Criteria

• all patients admitted to department of infectious diseases because of fever

Exclusion Criteria

• patents who refuse to sign informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Length of fever	1 month after admission	The interval between the onset of fever and the return of body temperature to normal after medical intervention or spontaneous remission

Secondary Outcome Measures

Name	Time	Method
Fever associated mortality	3 months	mortality of patients due to conditions associated with fever

Trial Locations

Locations (1)

Department of Infectious Disease, Xiangya Hospital, Central South University; 🇨🇳 Changsha, Hunan, China