Transfusion Recommendations Implemented in the PICU (TRIP)
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 200
- 试验地点
- 4
- 主要终点
- Mean change from baseline in transfusion recommendation adherence at 18 months (evidence-based threshold alert)
研究概览
简要总结
Evidence demonstrates that the risks of red blood cell transfusions outweigh benefits in many patients who are hospitalized in the pediatric intensive care unit with increased risk of organ dysfunction, infection, delirium, and death. Recommendations have been developed to restrict transfusion in patients who are unlikely to benefit; however, these recommendations have not been consistently adopted into clinical practice. This study examines use of targeted efforts (implementation strategies) to improve implementation of the recommendations, with a goal of reducing unnecessary transfusions and improving patient outcomes in critically ill children.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Employed at Lucile Packard Children's Hospital at Stanford University or the Children's Hospital of Philadelphia AND
- •Employed in one of the following roles:
- •PICU nurse
- •PICU attending
- •PICU fellow
- •PICU resident
- •PICU advanced practice provider
- •Other physician or surgeon in subspecialties whose patients regularly receive transfusions in the PICU
- •PICU TRIP implementation team member
- •PICU nursing leader
- •PICU physician leader
- •Bood bank leader.
排除标准
- •Unwilling to participate
- •Directly report to the primary investigator.
结局指标
主要结局
Mean change from baseline in transfusion recommendation adherence at 18 months (evidence-based threshold alert)
时间窗: 18 months
The investigators will assess the mean rate of nonadherent transfusions at monthly intervals in the pre- (12 months prior to CCDS tool initiation) and post-implementation period (18 months following CCDS tool initiation).
次要结局
- Mean change from baseline in transfusion recommendation adherence at 18 months (transfusions that require clinical judgement)(18 months)
- Reach of computerized clinical decision support (CCDS) tools(18 months)
研究者
Katherine M. Steffen
Clinical Associate Professor, School of Medicine, Department of Pediatrics, Division of Pediatric Critical Care Medicine
Stanford University