AKIN (Acute Kidney Injury Network): Acute Kidney Injury After On-Pump Coronary Artery Bypass Graft Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 817
- 主要终点
- To test the hypothesis that patients with acute kidney injury after on-pump CABG have higher 30-day mortality
研究概览
简要总结
The purpose of this study is evaluate clinical outcomes and 30-day mortality after on-pump CABG.
详细描述
Eight hundred and seventeen patients was enrolled in this series and divided into to groups: Group AKI (-) - patients without acute kidney injury after on-pump CABG. Group AKI (+) - patients with acute kidney injury after on-pump CABG. AKI was defined as an absolute increase in serum creatinine (SCr) of more than or equal to 0.3 mg/dl (≥ 26.4 μmol/l) or a percentage increase in SCr of more than or equal to 50% (1.5-fold from baseline). The change in SCr concentration was defined as the difference between immediate postoperative concentration and the highest concentration during the stay in ICU. Clinical Outcomes and 30-day mortality was evaluate in this patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients underwent on-pump coronary artery bypass grafting
- •Patients with at least two serum creatinine values within 48 hours.
排除标准
- •Patients with end-stage kidney disease requiring renal replacement therapy.
结局指标
主要结局
To test the hypothesis that patients with acute kidney injury after on-pump CABG have higher 30-day mortality
时间窗: 30 days
次要结局
- To compare clinical outcomes in patients with and without acute kidney injury after on-pump CABG(30 days)