Associations Between Psychological Factors, Pain Sensitivity, and Physical Function in Knee Osteoarthritis: a One-year Follow up Study

Ahram Canadian University1 site in 1 country150 target enrollmentJuly 15, 2023

ConditionsKnee Osteoarthritis

Overview

Phase: N/A
Intervention: Not specified
Conditions: Knee Osteoarthritis
Sponsor: Ahram Canadian University
Enrollment: 150
Locations: 1
Primary Endpoint: Change in Physical Function from Baseline to 1 year (WOMAC)
Status: Recruiting
Last Updated: 2 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

This study aims to determine if baseline measures of psychology and pain sensitivity can predict changes in physical function at 1 year in patients with knee osteoarthritis.

Registry

clinicaltrials.gov

Start Date

July 15, 2023

End Date

July 15, 2024

Last Updated

2 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Ahram Canadian University

Responsible Party

Principal Investigator

Mohamed Magdy ElMeligie

Lecturer of Physical Therapy and Director of Electromyography Lab

Ahram Canadian University

Eligibility Criteria

Inclusion Criteria

•Physician diagnosis of knee OA based on clinical and radiographic ACR criteria
•Pain in or around the knee on most days of the past month
•Aged 40 years or above
•Ambulatory with or without walking aid

Exclusion Criteria

•Inflammatory arthritis (rheumatoid arthritis, lupus, etc.)
•Recent knee injury or surgery (past 3 months)
•Severe comorbidity likely to prevent study completion (dementia, terminal illness)
•inability to comply with study procedures or follow up

Outcomes

Primary Outcomes

Change in Physical Function from Baseline to 1 year (WOMAC)

Time Frame: Change from baseline at 1 year

Assessed using the WOMAC physical function subscale (0-68 scale, higher = worse function)

Secondary Outcomes

Kinesiophobia(Change from baseline at 1 year)
Pain Catastrophizing Scale(Change from baseline at 1 year)
Change in Sleep Quality from Baseline to 1 year (Pittsburgh Sleep Quality Index)(Change from baseline at 1 year)
Change in Pain Self-efficacy from Baseline to 1 year (Pain Self-Efficacy Questionnaire)(Change from baseline at 1 year)