Study conducted to see the effect of swyambhuva guggulu vati and vatari taila in knee osteoarthritis.

Not yet recruiting

• Conditions: Bilateral primary osteoarthritis of knee. Ayurveda Condition: SANDHIGATAVATAH,

• Registration Number: CTRI/2022/09/045250
• Lead Sponsor: BVVS Ayurved Medical College and Hospital

Brief Summary

*Janusandhigata vata* is described under *Vatavyadhi in* all *Samhita*s*. Vata* is prime factor among all *Tridosha* and is responsible for all activities and manifestation of diseases in body. If *Vata* lodges in *Janusandhi* it can leads to manifestation of *Lakshana* like*, Shotha, Prasarana, Akunchana, Savedana,Sandhi-Stabdhata and Sandhi Atopa.*

This can be correlated to Knee osteoarthritis. Osteoarthritis is degenerative disease that involves peripheral joints in which there is damage to cartilage and as well as overgrowth of bone.

Knee Osteoarthritis is leading cause of chronic disability in developed countries; some 1,00,000 people in the United States are unable to walk independently from bed to bathroom because of osteoarthritis of the knee.3 Prevalence rate of knee osteoarthritis is 10%. Currently India has prevalence rate of 22% to 39% osteoarthritis which is diagnosed only by symptomatic cause and knee Osteoarthritis is 5.8%.

In contemporary science the management of knee osteoarthritis involves use of non-steroidal anti-inflammatory drugs, opiod analgesics and surgical interventions for control of symptoms.

All *Brihatrayi* and *Laghutrayi mentioned* *Snehana* treatment (*Bahya & Abhyatara*) as line of treatment in *Janusandhigata vata.**“Svayambhuva Guggulu Vatiâ€* which contains *Guggulu* as main ingredient which does the *Vedanasthapana* and contains drugs like *Vyosha, Chitrika*, etc. which are having *Tikta, Kashaya, Katu, rasa and Ushna Veerya which does Vatashamaka*. *Janu Basti* is a kind of *Snigdhasweda,* *Samshamaniya,* type of *Bahirparimarjana Chikitsa*.*Vatari Taila* which contains *Tila Taila* and *Eranda* does the *Snehana* there by *Vatahara* and due to *Ushnata Swedana* also takes place.  â€œHencethe present study is taken to evaluate the combined effect of *Swyambhuva Guggulu Vati* and *Vatari Taila Janu Basti* *in janusandhigata vata* with special reference to Knee Osteoarthritisâ€*.*

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2022-01-09
• Study Start: 2022-11-09

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• 1)Diagnosed patients of Janusandhigata vata (Knee Osteoarthritis).
• 2)Patients with the age group between 40 to 70 years of either sex will be selected.

Exclusion Criteria

• 1. Patients with Vatarakta, Amavata, Kroshtukashirsha etc.
• 2. Patients having traumatic, neoplastic and infections of knee joints.
• 3. Patients with other systemic diseases which interferes with treatment.
• 4. Pregnant and lactating women.
• 5. Osteoarthritis with structural deformity – genu varum, genu vulgum.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To check the effect of swyambhuva guggulu vati and vatari taila in janusandhigata vata with special reference to knee osteoarthritis	30 days

Secondary Outcome Measures

Name	Time	Method
To evaluate the efficacy of Swyambhuvaguggulu Vati and Vatari Taila in Janusandhigata vata with special reference to Knee Osteoarthritis.	30 days

Trial Locations

Locations (1)

Department of PG Studies in Kayachikitsa BVVS Ayurveda Medical College and Hospital; 🇮🇳 Bagalkot, KARNATAKA, India

Department of PG Studies in Kayachikitsa BVVS Ayurveda Medical College and Hospital

🇮🇳Bagalkot, KARNATAKA, India

Dr Ashwini Byali

Principal investigator

9902486104

ashwinibyali660@gmail.com