Assessment of Prognosis and Myocardial Reperfusion in Patients with ST-segment-elevation Myocardial Infarction (STEMI) According to Coronary Atherosclerotic Burden.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 2,200
- 主要终点
- All-cause mortality
研究概览
简要总结
In the current literature, it has been widely demonstrated that the extend of coronary atherosclerotic burden is associated with adverse long-term outcomes. Little is known about the impact of atheroma burden and either myocardial reperfusion and short-term outcomes after ST-segment elevation myocardial infarction (STEMI). Several angiographic scores have been used to measure the extend and severity of coronary atheroma. The SYNTAX score and the Gensini score have been shown to be independent predictors of cardiovascular events and mortality in stable coronary artery disease as well as in myocardial infarction.
This research therefore aims to assess the impact of overall coronary atherosclerotic burden, measured by two angiographic scores (SYNTAX score and Gensini score), both before and after primary percutaneous angioplasty, in patients with STEMI according to different clinical subgroups.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
All-cause mortality
时间窗: 2 years
all-cause mortality at 45 days, 1 year and 2 years
Recurrent acute coronary syndrome
时间窗: 1 year
Recurrent acute coronary syndrome at 1-year
次要结局
- All-cause mortality in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock(2 years)
- Recurrent acute coronary syndrome in patients with STEMI related to out-of-hospital cardiac arrest or cardiogenic shock(1 year)
研究者
Batric POPOVIC
Professor
Central Hospital, Nancy, France