The effect of the combined Transcranial Direct Current Stimulation with Task- Oriented Training on Electroencephalographic Biomarkers and involved upper limb motor function in hemiparesis post stroke

Iran University of Medical Sciences0 个研究点目标入组 36 人开始时间: 待定最近更新: 2022年11月21日

试验速览

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•Having a first unilateral ischemic stroke as confirmed by the MRI or CT-Scan
•At least 6 months have passed since the unilateral stroke
•Having the ability to walk for at least 10 meter (with or without cane)
•Having motor dysfunction in upper limb with a degree of recovery equal or more than 4 according to the recovery stages of Brunnstrom
•Having a score equal or above 26 in the Montreal Cognitive Assessment

•Having moderate to severe depression (a score of 19 or higher on the Beck depression scale)
•Received Botox in the previous 6 months (to enter the study, patients must not have received Botox in the past six months)
•Having a contracture in the wrist and fingers of the affected side
•Having other neurological disorders such as Parkinson, Multiple Sclerosis and etc.
•Having a thalamic stroke or central pain syndrome (Dejerine Roussy Syndrome)
•Pain in the affected shoulder (having a score of less than 12 based on the Pain Assessment section of the Fugle-Meyer assessment of the upper extremity)
•Using drugs that affect the central nervous system
•Having pace maker or other stimulation or ferromagnetic implants
•Having a history of Seizures in the last two years and taking anticonvulsant drugs during one month before the enrollment in the current study
•unwillingness and lack of cooperation to continue the treatment
•Having serious and persistent skin complications or sleep and concentration disorders due to stimulation with tDCs
•Not completing the treatment period or occurrence of an accident that affects the motor function or brain activity

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