To evaluate the efficacy and safety of regional block of the abdomen( between 2 muscles) using ultrasound guidance after laparoscopic nephrectomy surgery - a clinical trial
Not Applicable
- Conditions
- Health Condition 1: N998- Other intraoperative and postprocedural complications and disorders of genitourinary system
- Registration Number
- CTRI/2020/03/023760
- Lead Sponsor
- All India Institute of Medical Sciences Jodhpur
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
After approval from institutional ethical committee and written informed consent, patients belonging to American Society of Anaesthesiologists (ASA) physical status grade I and II, 18-65 years of age scheduled for laparoscopic nephrectomy will be included in the study.
Exclusion Criteria
Patients with infection at the block site, coagulation disorders, morbid obesity (BMI >40 kg/m2), allergy to local anaesthetic agent, major cardiac-respiratory disorders, severe renal or hepatic dysfunction, pre-existing neurological de�cit, psychiatric illness and excessive bleeding during the procedure will be excluded from the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare total fentanyl consumption (as rescue analgesic) during first 48 hours postoperativelyTimepoint: To compare total fentanyl consumption (as rescue analgesic) during first 48 hours postoperatively
- Secondary Outcome Measures
Name Time Method a) To compare Numerical Rating Scale (NRS) pain score <br/ ><br>b)To compare the duration of analgesia (time for request of first rescue analgesia after surgery) <br/ ><br>c)To compare patient satisfaction score <br/ ><br>d)To measure the CRP levels as a surrogate marker of stress response and pain transmission <br/ ><br>e)To compare any complications/side effect of block, catheter and drug <br/ ><br>Timepoint: NRS score - 0 hours,1,2,4,8,12,24,36 and 48 hours on rest and movement <br/ ><br>Time for first rescue analgesia after giving QL block <br/ ><br>Patient satisfaction score - Likert scale(1 to 5) <br/ ><br>CRP levels- pre operative <br/ ><br> 24 hours <br/ ><br> 48 hours <br/ ><br>Catheter related complications <br/ ><br>Catheter position - every 12 hours for misplacement/dislodgement