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临床试验/CTRI/2026/02/104391
CTRI/2026/02/104391尚未招募不适用

Comparison Of Clinical and Radiographic Outcomes of Calcium Hydroxide Based Obturating Material In Primary Teeth - An In Vivo Study

Dr KVasudha1 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2026年3月11日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
80
试验地点
1

研究概览

简要总结

Pediatric dentistry emphasizes the preservation of primary teeth until their natural exfoliation, and pulpectomy is the treatment of choice for primary teeth with irreversibly inflamed or necrotic pulp. Zinc oxide eugenol (ZOE), though commonly used, fails to meet these criteria due to its limited antimicrobial activity and delayed resorption. Calcium hydroxide, widely used in pediatric endodontics, possesses a high alkaline pH, sustained ion release, biocompatibility, aiding in halting internal resorption and neutralizing acidic environments; however, its use as a sole obturating material is limited by poor sealing ability, high solubility, inadequate resorption, and restricted antimicrobial efficacy. To overcome these limitations, combination pastes have been introduced. Iodoform exhibits strong antibacterial activity, particularly against anaerobes, resorbs faster, reduces tissue irritation, and allows easy placement in tortuous canals, while providing synergistic antimicrobial action when combined with calcium hydroxide. Natural additives such as curcumin and propolis further enhance the properties of calcium hydroxide

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
Participant Blinded

入排标准

年龄范围
4.00 Year(s) 至 8.00 Year(s)(—)
性别
All

入选标准

  • 1.Primary molars with irreversible pulpitis or nonvital pulp.
  • 2.Teeth with adequate root structure.
  • 3.Absence of periapical pathology.

排除标准

  • 1.Teeth with grossly destructed crown structures.
  • 2.Presence of internal or external resorption beyond repairable limits.
  • 3.Non restorable teeth requiring extraction.
  • 4.History of previous endodontic treatment.

研究者

发起方
Dr KVasudha
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr KVasudha

Sibar Institute of Dental Sciences

研究点 (1)

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