TO COMPARE THE EFFICACY OF BOWEL NOSODES WITH INIVIDUALISED HOMOEOPATHIC MEDICINES IN TREATMENT OF IRRITABLE BOWEL SYNDROME -SINGLE BLIND, COMPARATIVE RANDOMIZED CONTROLLED TRIAL STUDY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
Irritable bowel syndrome is a prevalent chronic functional bowel disorder characterized by abdominal pain or discomfort and altered bowel habits in the absence of detectable structural abnormalities. Diagnosis depends upon recognizing clinical symptoms pattern (using ROME III criteria) & no clear diagnostic markers exists due to it’s multifactorial nature of IBS . Severity of symptoms varies and can significantly hamper quality of life. Currently, there is no curative therapy; treatment is based upon symptoms control due to various pathophysiological Mechanisms that underline IBS subtypes. Bowel nosodes which are prepared from potentisation of Non lactose fermenting bacilli present in gut flora turn out effective for IBS. Bowels nosodes turns out effective in treatment of IBS because directly or indirectly it alter gut flora which turns out effective in improvement of IBS and thereby reduction in improvement of IBS-SSS value.
At the end of study it is expected that by using bowel nosodes in treatment of IBS helps in improvement of symptoms severity which is measured by using IBS - SSS score.
Also the improvement in patient’s quality of life is expected to get significantly improved which is calibrated by IBS-QOL questionnaire.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1 Patient fulfilling the ROME III criteria.
- •2 Patient who has a score of zero to 299 in IBS-SSS Score.
- •3 Patient of both sexes, all religion and socioeconomic status.
排除标准
- •1 Patients who had prior abdominal surgery which may cause bowel symptoms similar to IBS.
- •2 Patients with evidence of abnormal laboratory or imaging findings inconsistent with IBS.
- •3 Patients presenting with unintentional weight loss, rectal bleeding, family history of colorectal cancer onset at older age.
- •4 Currently participating in another trial studies.Patients with uncontrolled co-morbidites (hypertension, diabetes mellitus and hyperthyroidism) .
- •5 Pregnant females, lactating mothers and women who are planning for pregnancy in near future.
- •6 Patients who are not willing to participate in the study and currently participating in another trial studies.
- •7 Current use of long-term systemic steroids, immunosuppressants, or other therapies likely to interfere with the assessment of homoeopathic treatment outcomes.
研究者
Priyavani Panwar
National homoeopathic medical college , Lucknow