Evaluation of the Hypoalgesic Effects of Transcranial Direct Current (tDCS) in Combination With Motion Representation Tools in Healthy Subjects: a Double-blind Randomized Placebo-controlled Trial.
试验速览
- 阶段
- 不适用
- 入组人数
- 45
- 试验地点
- 2
- 主要终点
- Pressure pain threshold
研究概览
简要总结
The main objective of this research is to evaluate and quantify hypoalgesic effects caused by imagination and observation with or without the presence of transcranial direct current (tDCS) in healthy participants. The secondary objective of this research is to evaluate the possible relationships between hypoalgesic effects and different physical and cognitive variables such as the ability to generate motor mental images, mental chronometry and levels of physical activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •asymptomatic participants
- •men and women aged 18 to 65 years
排除标准
- •pregnant woman
- •use of painkillers in the last twenty four hours
- •presence of metal inside the head
- •pacemaker
- •wound on the area of electrodes' application
- •drugs consumer
- •recent application of transcranial direct stimulation
- •psychiatric disease who lead the subject to a misunderstand of the study
研究组 & 干预措施
transcranial direct current plus Brain training tools
20 minutes of transcranial direct current stimulation along with the application of motor imagery and action observation
干预措施: Sooma transcranial direct current stimulation device plus Brain training tools (Device)
Placebo transcranial direct current plus Brain training tools
A placebo intervention of direct transcranial stimulation being active during 15 seconds and then it will be turned off the rest of the time until 20 minutes. This group will also carry out the training of action observation and motor imagery.
干预措施: Placebo Sooma transcranial direct current stimulation deviceplus Brain training tools (Device)
Brain training tools in isolation
This group will act as a control, they will only carry out the training of action observation and motor imagery.
干预措施: Brain training tools in isolation (Behavioral)
结局指标
主要结局
Pressure pain threshold
时间窗: Change in Pressure pain threshold just before the start of the intervention, immediately at the end of the intervention and 15 minutes after the end of the intervention
Pressure pain threshold has been defined as the minimal amount of pressure at which a sense of pressure first changes to pain or discomfort
次要结局
- Ability to generate motor images(Just before the start of the intervention)
- Mental Chronometry(Just before the start of the intervention)
- The degree of physical activity(Just before the start of the intervention)
研究者
Roy La Touche Arbizu
Principal Investigator
Universidad Autonoma de Madrid