NCT01152944终止不适用
Mechanisms of Stroke in Intracranial Stenosis and Stenting
Jose Romano, MD1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2010年7月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Ischemic stroke in the territory of the stenotic artery
研究概览
简要总结
The objective of this SAMMPRIS-affiliated study is to understand the mechanisms the mechanisms that underlie ischemic stroke recurrence in high-grade intracranial atherosclerotic disease in order to determine predictors of recurrent stroke. MoSIS will evaluate 6 specific mechanisms of stroke in the medically-treated SAMMPRIS cohort: decreased antegrade flow, progression of stenosis, decreased proximal collateral flow, decreased distal collateral flow, impaired cerebrovascular reserve, and artery-to-artery embolism.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Enrolled in the medical arm of SAMMPRIS, signed consent
排除标准
- •For QMRA testing: contraindications to MRI; for TCD testing, abscence of ultrasonographic windows.
结局指标
主要结局
Ischemic stroke in the territory of the stenotic artery
时间窗: 2 years from enrollment
次要结局
未报告次要终点
研究者
Jose Romano, MD
Associate Professor of Neurology. Director of Cerebrovascular Division
University of Miami
研究点 (1)
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