ITMCTR2200006842
Not yet recruiting
Phase 1
Study on prevention mild to moderate Alzheimer's disease from exacerbating through invigorating spleen and kidney
onghua Hospital Shanghai University of Traditional Chinese Medicine0 sitesTBD
ConditionsAlzheimer's disease
Overview
- Phase
- Phase 1
- Intervention
- Not specified
- Conditions
- Alzheimer's disease
- Sponsor
- onghua Hospital Shanghai University of Traditional Chinese Medicine
- Status
- Not yet recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.The diagnostic criteria of Western medicine and traditional Chinese medicine for Alzheimer's disease was met;
- •2\.TCM syndrome differentiation belongs to the spleen and kidney deficiency type;
- •3\.Clinical dementia rating,Montreal Cognitive Assessment,Mini\-mental State Examination scale was used to screen patients with mild to moderate Alzheimer's disease (referring to CDR scale score of CDR score 1 or 2 patients 10 points \=MMSE score \< 27 points);
- •4\.Both men and women aged 50\-85 years old are acceptable;
- •5\.Informed consent was obtained from patients or their family members to voluntarily participate in this study.
Exclusion Criteria
- •1\.The diagnostic and inclusion criteria were not met;
- •2\.Patients with severe neurological deficits such as hemiplegia, aphasia, and visual and hearing impairment;
- •3\.Patients with cognitive impairment caused by other system diseases such as severe circulatory system, digestive system, urinary system, endocrine system and other diseases;
- •4\.Patients with underlying diseases affecting the oral absorption and metabolism of drugs;
- •5\.Patients with adverse addictions such as alcohol and drug abuse, psychotropic drug abuse and antidepressant drug abuse affected cognitive assessment;
- •6\.Patients with serious life\-threatening primary diseases and mental disorders;
- •7\.People with allergic constitution;
- •8\.Taking other cognitive\-improving Chinese medicine or Chinese patent medicine;
- •9\.Patients enrolled in other clinical trials within the past 3 months.
Outcomes
Primary Outcomes
Not specified
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