The relationship between age at menopause loci and the response of controlled ovarian hyperstimulation in women undergoing IVF: a candidate gene study.

Recruiting

• Conditions: Infertility; menopause; 10013356

• Registration Number: NL-OMON54409
• Lead Sponsor: Erasmus MC, Universitair Medisch Centrum Rotterdam

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 500

Inclusion Criteria

- A regular menstrual cycle
- Undergoing IVF because of male infertility or unexplained infertility
- First cycle IVF treatment
- Age between 18 and 45 years

Exclusion Criteria

- A history of ovarian surgery, chemotherapy of radiation therapy
- Non Northern European ethnicity

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary outcome parameter is the responsiveness of the ovaries to exogenous<br /><br>FSH stimulation during IVF treatment, i.e. number of retrieved oocytes. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study parameters are other outcomes of the IVF treatment, described<br /><br>by the number of follicles after stimulation, quality of retrieved oocytes,<br /><br>quality of embryo*s as well as pregnancy rate and live-birth rate.</p><br>