Efficacy and Safety of Rubus occidentalis extract on antihypertensive effect; A 8 week, Randomized, Double-blind, Placebo-Controlled Clinical Trial

The Catholic University of Korea, St. Vincent's Hospital0 个研究点目标入组 100 人开始时间: 待定最近更新: 2019年3月11日

适应症

试验速览

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•1)Male and female subject aged between 19 years and 70 years
•2)Subject with mean sitSBP 120~139 mmHg and mean sitDBP 80~89 mmHg at screening (at least 2 times measurements, 2-minute interval)
•3)Subject who agrees to participate in the study and signs the informed consent form

•1)Subject who cannot discontinue antihypertensive drugs
•2)Subject taking a drug influence of blood pressure (Steroid, Thyroid hormone, Contraceptive pills, Central nervous system depressants or stimulants, Angina pectoris drugs, Immunosuppressant, Blood Thinners etc.) over 3 months
•3)Subject with uncontrolled diabetes mellitus (more than 180mg/dl of fasting glucose at screening)
•4)Subject with severe cerebrovascular disease (stroke, cerebral infarction, cerebral hemorrhage) within 6 months
•5)Subject with severe heart disease (angina pectoris, myocardial infarction, heart failure, arrhythmia that needs medical treatments)
•6)Patients who are dependent on drugs or alcohol
•7)Subject with Creatinine = 2 times the upper limit of normal
•8)Subject with Aspartate Aminotransferase (AST) or Alanine Aminotransferase (ALT) = 3 times the upper limit of normal
•9)Subject who is pregnant, lactating or planning to pregnant during this clinical trial
•10)Subject planning to participate in the other clinical study
•11)Subject participated in any clinical trial within 3 months
•12)Inappropriate subject decided by the investigator

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