Sustainable reduction of antibiotics-induced antimicrobial resistance (ARena) in German ambulatory care

Not Applicable

Completed

• Conditions: on-complicated infections like upper respiratory tract infections, bronchitis, sinusitis, tonsillitis, and otitis media, and community acquired pneumonia and non-complicated cystitis; Infections and Infestations

• Registration Number: ISRCTN58150046
• Lead Sponsor: Federal Joint Committee (G-BA), Innovation Fund

Brief Summary

2018 Results article in https://www.ncbi.nlm.nih.gov/pubmed/29402306 results 2020 Results article in https://www.ncbi.nlm.nih.gov/pubmed/31921412 results (added 13/01/2020) 2020 Results article in https://www.ncbi.nlm.nih.gov/pubmed/32171252 results (added 17/03/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35279138/ (added 14/03/2022) 2018 Protocol article in https://pubmed.ncbi.nlm.nih.gov/29402306/ (added 22/08/2022) 2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33302559/ (added 22/08/2022) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34445964/ (added 22/08/2022) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34680732/ (added 22/08/2022) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36123597/ (added 20/09/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-09-13
• Study Completion: 2019-12-01
• Last Update Posted: 3 October 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30000

Inclusion Criteria

1. Healthcare professionals need to be part of one of the 14 participating practice networks in Bavaria and North Rhine-Westphalia and belong to one of the following medical specialist groups (Facharztgruppen, FG): GPs (Allgemeinmediziner, Hausarzt, hausätzlich tätiger Internist: FG 01, 02, 03), internists (Internist: FG 23), gynaecologists (Gynäkologe: FG 15, 18), ENT physicans (HNO-Arzt: FG 19), urologists (Urologe: FG 67), respiratory physicians (Pneumologe: FG 30,39,45), and paediatricians (Kinderarzt: FG 34, 40, 46)
2. Patients aged over 18, diagnosed with upper respiratory tract infections, acute bronchitis, sinusitis, tonsillitis, otitis media, non-complicated cystitis, or community acquired pneumonia by physicians in participating ambulatory practices and registered at AOK health insurance in Bavaria or North Rhine-Westphalia, Germany

Exclusion Criteria

Participants younger than 18 years and without German language skills will be excluded from survey and interviews

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antibiotics prescription rate in patients with non-complicated acute infections (upper respiratory tract infections, bronchitis, sinusitis, tonsillitis, and otitis media) within the three intervention arms, extracted from pseudonymized claims data each quarter year