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临床试验/NCT05809778
NCT05809778招募中不适用

Oral Lesions in Patients Dealing With Eating Disorders: an Epidemiological Study

IRCCS Burlo Garofolo1 个研究点 分布在 1 个国家目标入组 81 人开始时间: 2021年7月21日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
81
试验地点
1
主要终点
Prevalence of oral lesions in ED affected patients

研究概览

简要总结

Eating disorders (ED) are common among young. Anorexia (AN) and bulimia (BN) are the most prevalent ED. The American Psychiatric Association's guidelines state a 0.3% AN prevalence among young girls and a 0.1 to 4.2% BN prevalence. Men are not excluded: even if ED are more frequent in females (14-18 years), 1 man off to 10 can be diagnosed with ED. Unfortunately, the onset age is decreasing. In the last few years, always more preteens patients are diagnosed with ED: they generally refer a garbled self perception of body image. ED can have oral manifestations, such as: mucosal lesions, dental erosion, glandular hypertrophy, xerostomia and salivary disorders, dental caries These are the most common manifestations observed in patients with eating disorders, after a routine dental visit. There is not strong evidence that dental caries may be directly related to disordered eating habits; as a matter of fact results are controversial. Despite that, all the studies examined agree on the association between signs listed above and food disorders. Univocal percentages have not been reported in the scientific literature. For instance, a systematic review, dated 2016, showed that dental erosion is diagnosed in 45% of ED people, while other studies documented 70% patients affected by erosion. Another example reported is teeth hypersensitivity. According to some studies, 56% of ED patients reported such complaints, instead of other researches documenting 22% hypersensitivity impairment. As for dental caries, results are dissimilar. Authors showed 78% ED subjects diagnosed with dental caries. Other studies reported almost 50% patients with tooth decay, without statistically significant difference in the values between ED people and controls. All these differences are probably due to the different stages of eating disorders and diagnosis, and oral signs found. Different ages are also considered. The primary aim of the study is to evaluate the prevalence of oral cavity lesions among people affected by eating disorders.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Cross Sectional

入排标准

年龄范围
10 Years 至 18 Years(Child, Adult)
性别
All
接受健康志愿者

入选标准

  • Diagnosis of ED
  • Age between 10 and 18 years

排除标准

  • Parents or caregivers not understanding the Italian language
  • Patients affected by other systemic diseases

结局指标

主要结局

Prevalence of oral lesions in ED affected patients

时间窗: At baseline (day 1)

Mucosal lesions, dental erosion, glandular hypertrophy, xerostomia or other salivary disorders, and dental caries will be examined.

次要结局

  • To evaluate the association between presence of oral lesions and type of ED(At baseline (day 1))
  • To evaluate the association between presence of oral lesions and patients' global functioning index(At baseline (day 1))
  • To evaluate the association between presence of oral lesions and patients' self-perception about oral health(At baseline (day 1))

研究者

发起方
IRCCS Burlo Garofolo
申办方类型
Other
责任方
Sponsor

研究点 (1)

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