Evaluation of olive leaf extract in obese women on weight-loss diet

Not Applicable

Conditions: Obesity.
Obesity due to excess calories
E66.0

Registration Number: IRCT20190129042552N2

Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 70

Inclusion Criteria

Women aged 18-50 years
Body mass index 30-40 kg/m2

Exclusion Criteria

Menopause
Pregnancy and breast feeding
Food allergy
Having a history of cancer, acute or chronic renal Failure, acute or chronic hepatic failure, thyroid disorder and gastrointestinal diseases
Having surgical operation to weight loss
Having weight loss over the past six months
Consumption of multivitamin/mineral supplements, herbal supplements or weight-loss drugs
Don’t use more than 10% of medications

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Body weight. Timepoint: Before, after 4 and 8 weeks. Method of measurement: Scale.;Body composition. Timepoint: Before, 4 weeks and 8 weeks after intervention. Method of measurement: Bioelectrical impedance analysis.;Serum level of free fatty acid. Timepoint: Before and 8 weeks after intervention. Method of measurement: ELISA.;Fasting blood sugar (FBS). Timepoint: Before and 8 months after intervention. Method of measurement: Colorimetric enzymatic method (Pars Azmun).;Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Timepoint: Before and 8 months after intervention. Method of measurement: HOMA-IR: [fasting insulin Mu/ml × fasting glucose mg/dl]/405.;Lipid profile. Timepoint: Before and 8 months after intervention. Method of measurement: Colorimetric enzymatic method (Pars Azmun).;Serum level of leptin. Timepoint: Before and 8 weeks after intervention. Method of measurement: ELISA.;Serum level of adiponectin. Timepoint: Before and 8 weeks after intervention. Method of measurement: ELISA.

Secondary Outcome Measures