NCT04566055Unknown不适用
Assessing AlloSure Dd-cfDNA Monitoring Insights of Renal Allografts With Longitudinal Surveillance
适应症
试验速览
- 阶段
- 不适用
- 发起方
- CareDx
- 入组人数
- 1,000
- 试验地点
- 8
- 主要终点
- Validation of AlloSure in Allograft rejection
研究概览
简要总结
Prospective Observational Multicenter Cohort. External validation of donor derived cell free DNA in Renal Transplantation. Assessing performance of dd-cfDNA as a surveillance tool and its association with clinical outcomes. Outcomes include formation of de-novo DSA, eGFR decline, performance of AlloSure dd-cfDNA in Allograft rejection.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Renal transplant patients
排除标准
- 未提供
结局指标
主要结局
Validation of AlloSure in Allograft rejection
时间窗: October 2020
次要结局
- Performance of AS with De-Novo DSAs, Performance in subclinical and protocol biopsies vs clinically indicated for cause biopsies, Survival analysis considering AS surveillance(October 2020)
研究者
研究点 (8)
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