Hepatitis B Virus Reactivation: a Cautionary Event After Liver Transplantation for Patients With Hepatocellular Carcinoma
Completed
- Conditions
- Liver Transplant; Complications
- Interventions
- Diagnostic Test: Diagnosis of postoperative recurrence of liver cancer
- Registration Number
- NCT06114251
- Lead Sponsor
- Zhejiang University
- Brief Summary
Highly active hepatitis B virus (HBV) is known to be associated with poor outcomes in patients with hepatocellular carcinoma (HCC). This study aims to investigate the relationship between HBV status and HCC recurrence after liver transplantation. The study retrospectively analyzed HCC patients undergoing liver transplantation in 2 centers between January 2015 and December 2020. We reviewed post-transplant HBV status and its association with outcomes.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 920
Inclusion Criteria
- (1) preoperative diagnosis of HBV-related HCC and (2) pathologically confirmed HCC.
Exclusion criteria
- (1) non-HBV-related HCC; (2) simultaneous presence of other tumors; (3) re-transplantation; (4) presence of portal vein tumor thrombus; and (5) a survival time of less than 90 days.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description First Affiliated Hospital, Zhejiang University School of Medicine Diagnosis of postoperative recurrence of liver cancer - Shulan (Hangzhou) Hospital Diagnosis of postoperative recurrence of liver cancer -
- Primary Outcome Measures
Name Time Method Postoperative recurrence of liver cancer 2015.1.1-2020.12.31
- Secondary Outcome Measures
Name Time Method