NCT06114251已完成不适用
Hepatitis B Virus Reactivation: a Cautionary Event After Liver Transplantation for Patients With Hepatocellular Carcinoma
Zhejiang University0 个研究点目标入组 920 人开始时间: 2015年1月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 920
- 主要终点
- Postoperative recurrence of liver cancer
研究概览
简要总结
Highly active hepatitis B virus (HBV) is known to be associated with poor outcomes in patients with hepatocellular carcinoma (HCC). This study aims to investigate the relationship between HBV status and HCC recurrence after liver transplantation. The study retrospectively analyzed HCC patients undergoing liver transplantation in 2 centers between January 2015 and December 2020. We reviewed post-transplant HBV status and its association with outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •(1) preoperative diagnosis of HBV-related HCC and (2) pathologically confirmed HCC.
- •Exclusion criteria
- •(1) non-HBV-related HCC; (2) simultaneous presence of other tumors; (3) re-transplantation; (4) presence of portal vein tumor thrombus; and (5) a survival time of less than 90 days.
排除标准
- 未提供
结局指标
主要结局
Postoperative recurrence of liver cancer
时间窗: 2015.1.1-2020.12.31
次要结局
未报告次要终点
研究者
Xiao Xu
Professor
Zhejiang University
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