INTREPID - Deepening and Broadening knowledge of Psychoses Globally

Medical Research Council0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年4月1日

试验速览

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•Inclusion criteria for people with psychosis (cases ?):
•1. Age 18 to 64 years at the start of the case-finding period
•2. Currently resident in catchment area (primary residence)
•3. Presence of ICD-11 psychotic disorder, including substance-induced psychoses.
•4. Not treated with antipsychotic medication for more than one continuous month
•prior to the start of initial case identification
•Inclusion criteria for relatives:
•1. Age 18 and above
•2. Relative of an individual with a psychotic disorder who has consented to participate in the current study (either first-degree relative or other family member involved in care of the participating individual)
•Inclusion criteria for controls:
•1. Age 18 to 64 years
•2. Resident in catchment area (primary residence)

•Exclusion criteria for people with psychosis (cases ?):
•1. Transient psychotic symptoms resulting from acute intoxication as defined by ICD-
•2. Moderate or severe learning disability, as defined by ICD-11
•3. Clinically manifest organic cerebral disorder (e.g. infections, parasitic, toxic,
•cerebrovascular, epilepsy, brain injury), as defined by ICD-11
•Exclusion criteria for relatives:
•1. Insufficient contact with case to provide information on family burden or
•psychiatric history
•Exclusion criteria for controls:
•1. Past or current ICD-10 psychotic disorder
•2. Transient psychotic symptoms due to acute intoxication as defined by ICD-11
•3. Moderate or severe learning disability, as defined by ICD-11
•4. Clinically manifest organic cerebral disorder (e.g. infections, parasitic, toxic,
•cerebrovascular, epilepsy, brain injury), as defined by ICD-11
•5. Related to the matched case

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