A Prospective Observational Study of Sepsis

• Conditions: Sepsis
• Interventions: Other: no intervention

• Registration Number: NCT05309889
• Lead Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Brief Summary

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection and is associated with high morbidity and mortality. Sepsis3 gives sepsis a broad definition, reflecting the heterogeneity of the disease. So we need a precise treatment with a stratification of patient prognosis in order to reduce mortality in patients with sepsis.

Detailed Description

Not available

Study Timeline

• Status Verified: 2022-03
• Study First Submitted: 2022-03-30
• Study First Submitted QC: 2022-03-30
• Study First Posted: 2022-04-04
• Study Start: 2022-05-12
• Last Update Submitted: 2022-05-25
• Last Update Posted: 2022-05-31
• Primary Completion: 2023-05
• Study Completion: 2023-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 174

Inclusion Criteria

• Patients who met the Sepsis3 diagnostic criteria.

Exclusion Criteria

• Absence of laboratory test items (blood routine examination, coagulation function, liver function, biochemistry, urine routine examination, urine renal function, urine protein, etc.) >20%.
• Admission in ICU less than 48 hours.
• Patient with psychiatric disorders.
• Under 18 years of age.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
high exposure level	no intervention	Patients have a high level of exposure factors
low exposure level	no intervention	Patients have a low level of exposure factors

Primary Outcome Measures

Name	Time	Method
mortality rate	28 days after diagnosis of sepsis	all-cause deaths that occurred in 28 days

Trial Locations

Locations (1)

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; 🇨🇳 Guangzhou, China