The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 342
- 主要终点
- Alcohol consumption
研究概览
简要总结
The main purpose of this study is to investigate the region-specific cause of gallbladder stone incidence in Jeju Self-Governing Province, Korea.
详细描述
Investigators performed the epidemiologic study to uncover the reason of relatively higher incidence of Gallbladder cancer in small isolated island, Jeju island, one of small province among 11 self governing area in South Korea. Tow studies, including descriptive epidemiology and analytic epidemiology using case-control study, some risk factors were obtained regarding Gallbladder cancer development in this area. Old age, female, and gallstone were potential risk factors and alcohol consumption was preventive factors. So authors decided to evaluate the relationship between alcohol and gallbladder stone in order to how much portion of causal relationship they have with gallbladder cancer. So this study was designed to investigate the relationship between gallbladder stone and alcohol consumption then performed clinical based case-control study with age-sex matching to each subjects.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Clinical diagnosis of gallstone disease after cholecystectomy.
排除标准
- •Ambiguous diagnosis cases for gallbladder stone.
- •Incomplete medical record.
- •Control group
- •Inclusion Criteria
- •Healthy examinees in Health Promotion Center in same Institute
- •Eligible cases of abdominal ultrasound(US) or computed tomography(CT)
- •Exclusion Criteria
- •The case who was diagnosed as asymptomatic gallstone on abdominal US
结局指标
主要结局
Alcohol consumption
时间窗: Through study completion, an average of 1 year
Standard Dose Drink per week was used to compare the amount of alcohol consumption of each subjects
次要结局
- Obesity(Through study completion, an average of 1 year)
研究者
Byung Hyo Cha, MD
Gastroenterology Consultant, Representative of Digestive Disease Center
Cheju Halla General Hospital