Effect of single high-dose or daily low-dose vitamin D on muscle strength in older wome

Completed

• Conditions: Effect on muscle strength of vitamin D supplementation; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN14226530
• Lead Sponsor: Diskapi Training and Research Hospital

Brief Summary

2018 results in: https://www.ncbi.nlm.nih.gov/pubmed/30031389

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2016-02-01
• Study Start: 2018-07-04
• Last Update Posted: 20 August 2018

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 60

Inclusion Criteria

1. Healthy
2. Postmenopausal
3. Aged 50-68 years
4. Vitamin D level <20 ng/ml (50 nmol/l)

Exclusion Criteria

1. Individuals who had granulomatous conditions, thyroid disease, malabsorption syndromes, liver disease, kidney disease, diabetes or postural instability (cerebellar disease, vestibular disease, vitamin B12 deficiency, drugs)
2. Individuals taking anticonvulsants, calcium or vitamin D supplements, barbiturates, or steroids in any form

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
25OH vitamin D levels 3 months after treatment

Secondary Outcome Measures

Name	Time	Method
Muscle strength 3 months after treatment. Muscle strength tests were performed at 60° using a Biodex system 3 isokinetic dynamometer.