The Effect of Wearing Facial Masks on Skin Parameters During the COVID-19 Pandemic
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Transepidermal water loss change
研究概览
简要总结
The global coronavirus disease pandemic (COVID-19) has led to an increased need to wear protective equipment such as wearing face masks and practicing hygiene measures such as more frequent use of antiseptics. These measures can lead to changes in the skin, the development of new inflammatory skin diseases or exacerbation of existing ones, with health professionals especially under the risk of developing these changes. Changes in facial skin due to wearing masks have been observed in a number of studies, however, part of the study was based solely on subjects' self-assessment or clinical assessment, and only a small part on objective measurements of skin parameters. Also, the impact of prolonged masks' use have not been investigated.
The aim of these study was to investigate the effects of constant, long-term use of protective masks on facial skin.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •young, healthy volunteers who gave written informed consent - students of health related professions who wear facial mask for at least six hours a day durnig their internship/practice in health care institutions
排除标准
- •skin disease, skin damage on measurement sites
- •use of corticosteroids, antihistamines and immunomodulators a month prior the inclusion and during the trial
- •use of emollients three days prior the inclusion in the trial
- •non-adherence to the trial protocol
- •exposure to artificial and excessive natural UV radiation
- •pregnancy and lactation
- •skin cancer
- •immunosuppression
结局指标
主要结局
Transepidermal water loss change
时间窗: Weekly measurements for the duration of six weeks
Tewameter will be used to assess skin barrier function as a measurement of the water loss (g/hm2).
Skin erythema change
时间窗: Weekly measurements for the duration of six weeks
Mexameter will be used to assess erythema. It is a relative measurement and uses arbitrary units (AU).
Participants' reported facial skin changes
时间窗: Weekly measurements for the duration of six weeks
Structured interview to determine if participants developed adverse events related to mask wearing (such as dryness, erythema, rash, scaling, pruritus, pain/burning, changes in texture or colour, ulcers etc.) between two measurement time-points.
Stratum corneum hydration change
时间窗: Weekly measurements for the duration of six weeks
Corneometer will be used to estimate skin dryness. It is a relative measurement and uses arbitrary units (AU).
Melanin content change
时间窗: Weekly measurements for the duration of six weeks
Mexameter will be used to assess skin melanin content. It is a relative measurement and uses arbitrary units (AU).
Sebum level changes
时间窗: Weekly measurements for the duration of six weeks
Sebumeter will be used to assess sebum levels. It is a relative measurement and uses arbitrary units (AU).
次要结局
未报告次要终点
研究者
Dario Leskur
Assistant professor
University of Split, School of Medicine